New Class of Technology

Miro Technology utilizes electromechanical forces to actuate droplets on the surfaces of insulated electrodes, without requiring immersion in oil or direct contact with system electronics.

 
 

Broad Application

Because the system is compatible with a wide range of reagents, and also allows for an interface with conventional microfluidic channels, a wide range of applications is enabled on the system.

  • NGS library prep
  • Synthetic biology
  • DNA extraction
  • Combinatorial synthesis

 

How it Works

In Miro Technology, nanoliter to microliter droplets containing samples and reagents are manipulated by applying a series of electrical potentials to an array of patterned electrodes coated with a hydrophobic insulator. This technology is distinct from microchannel-based fluidics as it enables precise control of reagents without the need for complex channels, microvalves, or pumps.

How it Works

In Miro Technology, nanoliter to microliter droplets containing samples and reagents are manipulated by applying a series of electrical potentials to an array of patterned electrodes coated with a hydrophobic insulator. This technology is distinct from microchannel-based fluidics as it enables precise control of reagents without the need for complex channels, microvalves, or pumps.

 
 

Benefits

Because Miro Technology doesn’t require immersion in oil or (or another liquid medium) to mobilize droplets, and also does not require direct contact between the droplet and the electronics, there are numerous benefits when compared to other digital or conventional microfluidic approaches, including:

  • Compatibility with a wide range of reagents/solvents, e.g., ethanol and organic solvents
  • No unintentional extraction/diffusion into carrier oil
  • No electronics in consumable cartridge (enabling high-quality and highly-QC’ed electronics on the system)
  • Small and localized volumes enable fast ramping and tight temperature control
  • Freedom from oil enables automated interface with standard microfluidic channels to perform actions such as chaotic/pipette-like mixing without generating an emulsion
  • Ability to improve the kinetics of reactions by performing gentle mixing during incubations and other actions.

 
 

At Miroculus our mission is to advance science and improve lives faster, together.